The fused bodies of Luciela and Rafaela, The Destroyer is the most powerful of the awakened beings.
(Note: the name The Destroyer is only used in the English translation of the manga. This character is actually nameless in Japan)
In an effort to create the ultimate awakened being, Riful attempted to awaken the fused bodies of Rafaela and her sister the Abyssal Luciela of the South,
To induce the awakening, Riful kidnapped the Claymore Renee, and she and Dauf brutally tortured her into cooperation, but upon realizing what the sisters combined bodies would awaken into Renee made a desperate escape attempt, she escaped, but ultimately this did not prevent The Destroyers creation, Clare entered the mind of the sisters and accidentally triggered their awakening.
An unlikely alliance then ensued between Clare and her arch-enemy Priscilla, who together defeated The Destroyer, but at a high cost, the pair were trapped within the remains of The Destroyer's body, and though the Claymore believe it is possible to free Clare, they can not do so without also freeing Priscilla, and thus made the hard decision to leave Clare within the Destroyer's body.