Rose is a young Red Dragon who is being looked after by Eriko Nanao and Ryuji Kisaragi, a young man whom she fell in love with at first sight.
Being a dragon, Rose was developed inside of an egg until hatching. When she hatched, the first thing that she saw a young boy who had gotten separated from his parents during an expedition to locate Lost Preciouses. Having startled the child, he slipped and began to fall from the cliff that he was climbing. Rose rescues the young boy and these experience permanently imprint him into her memory.
Sometime after hatching, Rose was captured and was in the process of being sold but was rescued by Seven Tails, led by Eriko Nanao and her cousin/first employee Ryuji Kisaragi. During the ensuing battle between Seven Tails, the buyers, and the sellers, the package containing Rose is accidentally opened by Ryuji Kisaragi and Rose falls out. To her surprise, she sees the same young boy that she saw when she first hatched, Ryuji, and immediately falls in love with him. After escaping, Ryuji and Eriko decide to take care of Rose and she moves in with them.
In the time between her hatching and meeting Ryuji and Eriko, Rose became engaged to a black dragon and member of Fang known as Onyx. While being examined at a Society facility, Onyx wages an attack and is able to capture her. Back at his compound, he explains the situation to Rose who seems to be completely unaware of it. Despite her loss of memory however, she wears a Lost Precious necklace that Onyx gave her a long time ago as an engagement present. Resigning herself to her fate, Rose agrees to go along with Onyx's plan but is rescued by Ryuji when he destroys the necklace and defeats Onyx with Rose's help.