Refrain is a anime/manga thing
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Refrain is a potent and highly addictive psychotropic narcotic that spread through much of Area 11. Use causes a person to relive the happiest memories in their life.

General Information Edit
Thing Name Refrain
Japanese Name: リフレイン
Romaji Name: rifureen
1st manga book:
1st anime episode: Code Geass: Lelouch of the Rebellion #8
1st anime movie:
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