"Enuma Elish!" - anti-world Noble Phantasm which rips throough reality.
It perhaps needs the condition of him being serious though.
He has the All Seeing Eye( deputed in Fate/Hollow Artaraxia) which anables him to read thoughts and see the structure of almost anything.
His Gate of Babylon holds incredible amount of Noble Phantams...exceptionally powerful weapons with usually some kind of special ability or two.
His golden armor should be able to survive a punch or maybe even 10 of them. Not to mention he can turn into spirit form to avoid any kind of attack.
He has a huge flying ship with the speed of thought called Vimana and the very chains he used to ensare the Heavenly Bull in his legend(which he calls ironically Enkidu now)
And lastly EA. A sword attained from the Underworld believed to be older than the world itself. It's blast creates a false layer of space and time to attack and used in full power it has the threat of possibly breaking down the whole universe(probably not with the blast, but with messing up reality).
And those are only the Noble Phantasms we know of.
Perhaps if he stays in the "die in laughter, mongrels attitude" he hardly has a chance...especially because he's a villian while Superman is a hero...so he has a certainly thin plot armour.