@Falbium_Asmodeus: Ophis is nothing to the likes of Zonge-sama, Toph with ScrewAttack logic, the Uchihas, or even Zabuza, whose sword cannot be beat!
Lol but on a serious note, I think the following could be a good match up for Ophis (Kamen Riders because I've been having a Kamen Rider phase lately lol):
Man of the Beginning (Kamen Rider Gaim) - closest one as he, at least from what I have seen, the strongest main Kamen Rider by leaps and bounds. So powerful that he pretty much makes every other Rider look like chumps
Hyper Kabuto (Kamen Rider Kabuto) - only via time travel
Final Form Decade/Manga Decade (Kamen Rider Decade) (Note: the difference between manga and canon Decade is that manga Decade can use multiple Rider powers at once, for example, using Rising Ultimate Kuuga's planet level+ Rider Kick while Hyper Clocked Up, or so I've heard)
Super Climax Den-O (Kamen Rider Den-O) - only via time travel
This isn't even getting into the Overlord of Darknes and the Overlord of Light, the former realigning the Scorpio constellation to bring life back to Earth.