Lanister is weak what about Drogo or Ned
Pretty sure both at their prime could easily overpower him
In a purely physical fight, it depends. I mean you if level up the Dovahkiin enough and get him the right equipment; he can beat down Dragons and Deathlords with his fists, albeit with some good gauntlets. It depends on how you interpret it, but if we take gameplay feats into account then he probably beats them too. If it is a fight with just their bare fists, and nothing else, it could go either way.
If the Dovahkiin has his magic and shouts it wouldn't really be fair, so exclude them for those two fights.
Those fights would also be much more awesome than this one. Ned was an honorable man and had an epic beard, and Drogo was hardcore and treated his lady right; moral ambiguity and pillaging aside. Why couldn't Jaime have died instead of them?