Naruto characters (Well a few like Gai, Raikage, Bee, Minato) are bullet timers, the rest can dodge a few bullets but not rapid fire, if deadpool is fully armed Sasuke goes down, he wont even know what a gun is,Sasuke would lose this , deadpool is an extremely gifted fighter , far far more skilled then spiderman , his regeneration is on a par with people like wolverine and black tarantula . He can regenerate whole organs and even severed limbs.He has been depicted as surviving decapitation. The head did not regenerate though, rather, it was simply replaced and healed back to his torso.Weapon X heightened his powers to a point where he was able to regrow body parts at will - better and stronger than before, enabling him to regenerate a severed arm in mere seconds.
Deadpool can also reanimate (that is, come back from the dead), as a direct result of his healing ability. The reason for this is unknown. In fact he has died and come back to life like this 3 times.As a by-product of his healing factor, he possesses enhanced strength, agility, and reflexes.His body is in a constant state of flux and regeneration due to cancer that he has , which keeps his regeneration constantly working , Deadpools brain cells are similarly affected, rendering him immune to psychics such as Professor X, Cable and Emma Frost.
Aside from his physical advantages, Deadpool is a superb assassin and mercenary, and an expert in multiple forms of armed and unarmed combat and possesses excellent skills of marksmanship.He also owns a personal teleportation device, usually located on his belt.
Deadpool singlehandedly engaged a group of five other superheroes including Goliath, Captain America, Hercules, Falcon, and Iron Fist (disguised as Daredevil) in hand-to-hand combat, though the outcome of the battle was forestalled by Captain America and the arrival of Cable. The combination of his battle-prowess and enhanced physique enabled him to defeat the non-superhuman grandmaster combatant, the Taskmaster, while both his hands and feet were manacled. Deadpool believes Taskmaster had let him win, but he later reveals to Deadpool he hadn’t.
hes completely insane and he becomes more insane every time he dies, to the point of psychopathy and hallucinations , he talks in 3rd person and also out of character like he addresses the reader and remarks on how his speach bubbles are yellow ,Deadpool uses his continuous, off-the-wall banter to distract, insult, frustrate, and infuriate his opponents. Even when losing, he has refused to keep quiet and his constant chatter has even slightly muddled Daredevil’s enhanced senses. Its claimed this is the most dangerous aspect of his combat style, since he can appear to be completely distracted and disorient his opponent while still focusing on the battle.
Not only that but Deadpool from time to time has proven to be able to tank hits from 100 tonners and took a nuke at one point, teleportation ect buttles, all Sasuke has is speed, Susanoo, and Genjutsu (Which arguably wont work on Deadpool)