Since a young age, Itachi's intellect and talent have shown their brilliance in everything he did as even his teachers said his progress hardly required any help. In the few battles he has been seen in since the start of the series, Itachi was shown to be an extraordinarily powerful ninja, and easily one of the strongest shinobi in Naruto, as demonstrated by his ability to easily defeat Deidara and Kakashi Hatake, as well as having his skill praised by several people including Madara Uchiha and Orochimaru. By the time he was 13, he was already the most powerful ninja in the Uchiha Clan. Even when battling with a clone that had about thirty percent of his power, his skills allowed him to still be evenly matched with Kakashi and Naruto in Part II. He has demonstrated tremendous skill in all 3 forms of ninja combat. He is a master of the Sharingan, as he has demonstrated great talent with its abilities, such as its unique Genjutsu throughout the series. When faced with an opponent's Genjutsu, Itachi can use his Sharingan to dispel it or perform Demonic Illusion: Mirror Heaven and Earth Change and turn the Genjutsu against its user. Itachi is also noted to be very fast, both in his ability to maneuver and accelerate(when fighting Kurenai and Kakashi) along with his movements such as hand seals. Kakashi, an elite Jonin-Level ninja and fellow user of the Sharingan, had great difficulty keeping up with his speed as he couldn't see Itachi form any hand sign's when he proformed a jutsu. . Sasuke later commented on this speed in Part II during his fight with Itachi, since Itachi was capable of forming hand seals without them being noticed by Sasuke, while he was throwing multiple shuriken and defending Sasuke's attacks at the same time. Itachi also possesses the Mangekyo Sharingan, which increases his already great power, and enables him to use his most powerful techniques. With his left eye, he can use Tsukuyomi, a Genjutsu that traps an opponent's mind in an illusionary world, torturing them for what seems like days in a matter of seconds. With his right eye he can use Amaterasu, a Ninjutsu which allows him to create a black flame that he can direct with his eyesight to burn through almost anything in its path. His final technique is Susanoo, a technique that manifests as a spectral being made of chakra resembling a yamabushi with a tengu mask surrounding his body. It wields the Totsuka Sword, a spectral sword with the ability to bind what it cuts into an alternate dimension, trapping it in a Genjutsu state forever, and Yata's Mirror, a shield that can reflect many attacks. Zetsu, a fellow Akatsuki member, states that Itachi's mastery of the Sharingan's Eye Techniques and Genjutsu makes him invincible. Despite his mastery of the Mangekyo Sharingan, Itachi is falling prey to its side effects, as his eyesight is worsening after every activation and he will eventually go blind from its power, and his Sharingan will be forever sealed away.
In terms of standard Ninjutsu, Itachi can create shadow clones to perform techniques for him and act as shields from attacks. These clones can also be commanded to explode with Clone Great Explosion. As a member of the Uchiha clan, he can also perform "Fire Release: Great Fireball Technique" to catch opponents in a blast of fire, and in the anime can breathe multiple fireballs with Fire Release: Phoenix Immortal Fire Technique. With Water Release: Water Fang Bullet he can also catch targets in a circle of crushing water
As the leader of Akatsuki and one of the two sides of the Amegakure Civil War, Pain is an extraordinarily powerful ninja that can easily be considered Kage-level; his partner Konan has stated that he has never lost a fight. He was able to single-handedly defeat and overthrow the former Amegakure leader, Hanzō, and made short work of Jiraiya after unveiling all six of his bodies (though Pain admitted that killing Jiraiya would have been very unlikely had Jiraiya had prior knowledge of his six separate bodies).
Pain has been seen using many highly advanced techniques like the Shapeshifting Technique, which allows him to clone Akatsuki members using human sacrifices that they control and can use to engage enemies in place of themselves. The clones formed are perfect copies of the original, possessing any unique genetic traits or weapons they may possess. The clone's abilities are proportionate to the amount of chakra given to the clone.
His most important technique in regards to Akatsuki operations is the Illusionary Dragon Nine Consuming Seals. With the other members of Akatsuki, this technique begins a three day trial to forcibly extract the Tailed Beast from its host and forces it into a giant statue. There seems to be a order on which Tailed Beast they can seal at once as they are unable to seal the Nine-Tailed Fox without sealing the other beasts as it would destroy the statue, possibly freeing all the captured beasts.
It also enhances his vision in a similar manner to the Hyuga's Byakugan, allowing him to see through solid objects and sense the chakra of barrier techniques as well as give tremendous analytical powers like the Uchiha's Sharingan.
Genius: When Gin was younger he was hailed as a child genius. He was highly proficient in his classes at the Shinigami Academy and therefore he graduated far ahead of those around his age and gained a seated position in the 5th division while still a child.
Master Swordsmanship Specialist: Gin is a highly proficient combatant. In combat he doesn't seem the least bit taken back by the abilities of his opponent, even when they seemingly have an advantage. He fights with seemingly no effort behind his attacks. His ability to wield his combat skills where evident even when he was a child. He easily defeated and killed the former third seat of the 5th division, who by rank should have been more powerful and skilled then him.
Flash Steps Master
Shinso (神鎗; lit. Divine Spear, Viz: Sacred Spear): It looks like a wakizashi (Japanese short sword) normally and the guard is shaped like an 'S'.
Shikai Special Ability: In its Shikai, Shinsō's blade glows white and extends at high speed to impale Gin's opponents from a distance. The blade also carries tremendous force when extending, as seen when Gin pushes both Ichigo Kurosaki and the giant Jidanbō out from under the Seireitei gate, despite the latter being firmly braced under it. In addition, Gin can maintain the extension and swing the activated Shinsō in wide arcs, attacking multiple targets quickly and simultaneously.
Bankai: Not Yet Revealed