Dengeki has what they're calling the first drawings of both Horo and Lawrence for Spice and Wolf II. This is more exciting because it means that the sequel is finally moving forward than because of the drawings themselves, which look more or less like the first season's versions. The first season started in January '08. I kind of doubt we'll see it as soon as Spring '09, though I suppose it's possible...summer or fall is more likely, though sometimes they like to keep a show in the same season, so we might not see it until January '10. (I'm crossing my fingers that we get it earlier, though.)
The article also notes that while the novels that the series was originally based on, by writer Isune Hasekura and illustrator Juu Ayakura, are still going strong (the 9 was recently released), the manga adaptation by Keito Koume has been slumping a bit.
The official Spice and Wolf website also talks about the second season, by which I means it has some of the staff mentioned: director Takeo Takahashi and script writer Naruhisa Arakawa are back, as are voice actors Jun Fukuyama (Code Geass's Lelouch) as Lawrence and Ami Koshimizu (Geass's Kallen) as Horo.

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"Generic" Saber Figure comes as a Pack-in with PSP Game
Fate/Extra! indeed.
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The Daily Drill: Gurren Lagann Episode 02
Drill on!
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WTF Wednesday: Tube Dubber
Your life will change forever.
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The Daily Drill: Gurren Lagann Episode 03
Title: You Two-Face Son of a Bitch!
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Hatoyama Wants to Make it Easier For Foreigners to Live in Japan
*packs bags*
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| It's Like Fame-- Ninja-Style |
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Google Translate: How Well Does It Do Now?
This won't do your Japanese homework just yet.
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Straight Up News 11/16/09
Everything you need to know from the last 7 days in one easy package.
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"Generic" Saber Figure comes as a Pack-in with PSP Game
Fate/Extra! indeed.
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The Daily Drill: Gurren Lagann Episode 02
Drill on!
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Otaku Offically Makes a DS his Waifu
*salutes*
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| It's Like Fame-- Ninja-Style |
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WTF Wednesday: Tube Dubber
Your life will change forever.
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Hatoyama Wants to Make it Easier For Foreigners to Live in Japan
*packs bags*
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Straight Up News 11/16/09
Everything you need to know from the last 7 days in one easy package.
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Gurren Lagann: Before and After the Movies
O M G
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on Dec. 22, 2008