this interesting visual project of Lady Gaga's, in which she did this photoshoot which focused on disabilities-- it's not the first time she did, either, as similar themes appear in her Paparazzi video, and her performance at the VMA Awards.
"So what, Gia?" you're thinking. "I mean, sure, Lady Gaga is something of a Japanophile, but what does this have to do with me?"
Rei Ayanami in Evangelion. You could also offer up Abiru Kobushi, the frequently injured tail-pulling girl in Sayonara Zetsubou-sensei, or even Chii in the introductory episode of Chobits (pictured left).
So, is Lady Gaga the first American kegadoru? Maybe!