Guren is tasked with capturing the Three-tailed Bijuu by Orochimaru. She has the Kekkei Genkai of Crystal Release
After Kimimaro's illness was discovered, Guren was given the opportunity to become Orochimaru's next vessel. However, she was unable to reach him before he was forced to chose another body. At this time, Orochimaru began training Sasuke to be his next vessel, which upset Guren greatly.
She agrees to capture the Three-tailed Bijuu in order to prove her worth for "becoming one with Orochimaru". She eventually fails at this after becoming attached to a young boy named Yukimaru who could control the beast at the expense of his health.