A group of assassins formed by Knives and led by Legato. Their goal is to cause endless suffering to Vash the Stampede.
The Gung Ho Guns are a group of assassins that were gathered by Millions Knives with the sole purpose of causing mental and physical pain to Vash the Stampede. The team is lead by Legato Bluesummers. Each member of the group was at one point human, but each gave up their humanity in order to achieve great power. Their purpose in the manga differs slightly from the anime version of the Gung Ho Guns. While their goal is to cause Vash suffering, Legato makes it a priority to play a game where each Gun carries a coin half and Vash has the other halves of the coin. Legato claims that something interesting would happen if Vash collected all the coins. He also tries to use the Guns to kill Vash, but Knives interjects and stops them from doing so.
Status: Killed by E.G. Mine for his failure.
Dominique the Cyclops is the only female member of the Gung Ho Guns in the anime. She has purple hair and dresses similar to a 1950s detective. Her main weapon is what she refers to as a Demon's Eye, her right eye which she keeps covered with a metallic eye patch. With her weapon, she is able to teleport instintanouesly from one point to another, getting in an enemy's weak spot and killing them. She is first seen laying waste to a group of thugs called the Roderick Gang before being asked by Legato to take care of Vash. When Vash gets to town and sees the dead bodies, Dominique introduces herself as she goes on the attack. Even with Vash's highten senses, he is unable to keep up with Dominique. After a few warps, he figures out that she is not moving fast but the Demon's Eye slows down his nerves and she is able to get around him. He removes himself from the illusion by focusing all of his attention on pain and is able to wound Dominique. Before Vash can continue the assault, Millie and Meryl show up to chastise Vash for attacking a woman and go to check on her. Dominique uses the opportunity to flee and heads back into town only to encounter Midvalley the Hornfreak.
Status: In the anime, she is killed by E.G. Mine for her failure. In the manga, she commits suicide by jumping off of a cliff.
E.G. Mine is an assassin whose primary weapon is an iron ball that he hides in. By using a variety of strings and wires in this suit, he is able to launch spikes at opponents at an amazing speed. He can also use his iron ball as a defensive shell against enemy attacks. He was revealed along with the rest of the Gung Ho Guns that killed off dozens of gang members and was the third assassin to meet with Vash. After Vash had cleared a town of all its people from a fear of innocents getting caught in the crossfire, he comes across the corpses of Monev and Dominique. E.G. Mine reveals that he killed them and will do the same to Vash. When Vash attempts to shoot E.G., he laughs it off saying that no one can penetrate his shell. What he failed to notice was that Vash had aimed at his various threads which severed and E.G. lost his weapon.
Status: In the anime, he is killed by Rai-Dei the Blade for his failure. In the manga, he is killed by Legato for the same reason.
Rai-Dei the Blade is a samurai assassin who adorns the typical clothing of an ancient samurai. He is able to unleash torrents of wind when he slashes his sword, causing anything in its path to be blown away or crushed in the process. He is the fourth assassin to encounter Vash after his battle with E.G. Mine where he kills his comrade after his failure, right in front of Vash. Vash criticizes Rai-Dei for killing his comrade, but the samurai points out that failure is not an option and those who fail will be punished. Vash tries to battle with Rai-Dei, but the powerful attacks from his sword render his attacks useless. When it appears that Rai-Dei has Vash cornered, Legato taps into Vash's body to unleash the Angel Arm. Rai-Dei flees in confusion as Vash is able to point the attack upwards but still destroys the city as a result. When the smoke clears and the attack subsides, Rai-Dei is revealed to be alive and meets with Wolfwood. He begs to the priest that they have to go after Vash, but Wolfwood claims that that is not an option.
Status: Killed by Wolfwood after his encounter with Vash.
Leonof the Puppetmaster is an elderly man who dresses in a classical suit with small glasses and walks around with a suitcase. His powers lie in his ability to create puppets that look as real as an actual person. He can also graft puppet pieces together to form monsters and creatures to attack his enemies. Leonof can manipulate dozens of puppets at once with a red jewel attatched by strings to his fingers. While Leonof and Vash never met face to face, he was the next Gung Ho Gun that Vash would battle with on a highjacked Sand Steamer. The ringleader of a group was threatening to kill the passengers of the Steamer, but Vash appeared to save the day. This ringleader was a puppet of Leonof's and returned to his master with the news of Vash's return. He would then follow Vash to a floating airship above the clouds and launch an attack on the people in the ship along with Hoppered the Gauntlet and Gray the Ninelives. Although he never appeared on the ship, he sent dozens of puppets to look like the ship's residents and attack Vash, letting his humanity get in the way. Leonof comes the closest to killing Vash with a puppet that resembled his friend but was saved by Wolfwood at the last minute.
In the manga, it is revealed that Leonof's real name is Emilio and that heknew Vash when he was a child and had a fondness for puppets, particularly one that looked like a girl he was enamored with. It takes Vash a while to get through to him as Leonof's puppets begin to fall off the ship they are in. Leonof goes after the puppet that resembles his loved one as his puppet strings are attatched to a deck above him and his puppet below. Vash attempts to pull Leonof up by the strings but is stopped by a spider puppet.
Status: In the anime, Leonof was killed by Wolfwood for almost killing Vash. In the manga, Leonof falls to his death as he chases after his favorite puppet.
Hoppered the Gauntlet is one of the more bizarre members of of the Gung Ho Guns. He is deformed greatly as he uses his large arms and a weight to walk around a large metal top to spin and attack enemies. He meets Vash during an attack on a sky ship with a triple attack alongside Leonof the Puppetmaster and Gray the Ninelives. He primarily battles with Vash as he uses his top to get the upperhand many times before Gray is able to cause the core of the ship to explode. Vash is able to escape the core as Hoppered stays behind.
In the manga, Hoppered explains that he seeks to avenge a woman he cared about that Vash killed during the crisis in July. However, during the fight, he has a revealation and realizes that Vash is not to blame. He attempts to aid Vash in his attacks against the Gung Ho Guns but this fails.
Status: In the anime, he is killed from the explosion in the energy core. In the manga, he is killed by Legato for aiding Vash
Gray the Ninelives is the largest and one of the deadlier members of the Gung Ho Guns. He appears to be a fifteen foot muscular man who can easily crush and destory anything in his path. His nickname Ninelives comes from the fact that nothing can kill him. He launches a three man attack with Hoppered the Gauntlet and Leonof the Puppetmaster on a Sky Ship Vash and Wolfwood were visiting at the time. Since Hoppered and Gray are on two ends of the ship and trying to destroy two cores, Wolfwood and Vash split up. When Wolfwood encounters Gray, he tries to do everything he can to stop the mountain of a man. It takes several rockets from his Cross Punisher to slow down Gray. It is then that we see that Gray is actually a cyborg with a human brain surrounded by a metallic shell. While Wolfwood is able to stop his torso, Gray's legs continue and destory the ship's core and cause the ship to collapse.
In the manga, Wolfwood discovers that Ninelives comes from the fact that Gray is composed of nine dwarves who operate the machine as if it were a mecha of sorts. Wolfwood is able to take care of most of the dwarves but they are still able to blow up the ship.
Status: In the anime, Gray is killed from a combination of Wolfwood and the exploding core. In the manga, Wolfwood is able to kill seven of the nine dwarves and two escape.
Zazie the Beast has two different representations in both the manga and the anime. In the manga, Zazie is actually a collective hive of insects that possess the body of a young boy and later a young girl. They agree to work with Knives since they want to see whether it is better to co-exist with Humans or Plants. In the manga, Zazie does everything it can to kill Vash but is thwarted by Hoppered who is working with Vash. The second time Zazie possessed a human girl, it tried again to kill Vash but was ultimately defeated by Legato.
In the anime, Zazie is a demon that takes over the body of an orphan whose parents were killed by Knives. By using a super sonic device, he is able to manipulate sand worms to hone in and attack the group of orphans and Vash's group in an abandoned town. Vash realizes soon after who Zazie is and is able to destory the device and confront Zazie. Zazie then withdraws a revolver and is ready to do battle with Vash before Wolfwood interupts the fight.
Status: In the anime, Zazie is killed by Wolfwood. In the manga, the collective hive of Zazie is killed by Knives.
Caine the Longshot is an enigmatic member of the Gung Ho Guns. He is a mute man who walks around in a cowboy outfit and a mask. One of his eye holes is closed with the other open. He is a sniper specialist who is able to snipe from ranges that can be equated to in miles. Caine sets up shop outside of an abandoned town that Knives and Legato cleared out by killing its inhabitants. He goes after Vash with his fifty foot rifle as Chapel the Evergreen goes after Wolfwood. It takes Vash a while to realize that Caine is in the outskirts of town and drives to meet with him. Caine repeatedly tries to gun Vash down, but after adjusting his sight, he finds Vash gone. Vash, using his senses and speed, is able to disable Caine's sniper rifle with his machine gun and asks Caine to simply walk away.
Status: Committed suicide after being defeated by Vash. Vash builds a grave with Caine's equipment out of respect for the dead Gun.
Chapel the Evergreen is a member of the Gung Ho Guns who has a reputation for being sloppy and tardy. Even when he was supposed to meet with Legato and the rest of the Guns, he did not show up. Chapel is a priest who dresses in black and wears red goggles that are attatched to his face. His main weapon is similar to Wolfwood's Cross Punisher, only it is able to split into two seperate machine guns. He is Wolfwood's former mentor after Wolfwood killed his abusive guardian. Chapel first arrives in an abandoned town where Vash's group has set up camp. He tells Wolfwood that due to his success with monitoring Vash that he would be the next Chapel the Evergreen. However, Wolfwood wants no part in this and fights with Chapel. Although Wolfwood tries to walk away, Legato manipulates Chapel to wound Wolfwood that would lead to his death. Chapel later encounters Legato and Midvalley to avenge Wolfwood's death.
In the manga, Chapel the Evergreen is actually Wolfwood. He stole the title from his former master after paralyzing him and taking the Cross Punisher for himself. He is charged by Knives to accompany Vash to ensure his overall survival as well as ensuring that he suffers as well. He is also a part of a group called the Eye of Michael that trains assassins and two other members are a part of the Gung Ho Guns. Because of this training, Wolfwood has access to formulas and potions that allow him to regenerate and last in battle. In the end, Wolfwood kills the real Chapel and later overdoes and dies.
Status: In the anime, Knives kills Chapel with a dark void after Chapel attempts to kill Legato. In the manga, Wolfwood breaks Chapel's neck.
Midvalley the Hornfreak is the one of the last assassins of the Gung Ho Guns Vash encounters. He wears a purple suit and carries around a saxophone which is his main weapon. He can synch up shounds from his instrument to cause pain reciptors in a person's body to act up. He can also blast sound waves at people and destroy any object in front of him, similar to Rai-Dei's weapon. He meets Vash in a town as he begins to attack Vash. Since his plan does not work, he double teams with Legato to cause Vash pain whereas Legato would cause an innocent person to walk out into the open and Midvalley would shoot at them. Vash would then step in the way of these attacks and take the blows. He eventually crippled Midvalley by using a bullet to knock out the B flat note on his saxophone. Midvalley tries to attack again with a hidden gun in his instrument but this does not work either.
Status: Committed suicide after his failure. In the manga, he is killed by Legato.
Legato Bluesummers is the de facto leader of the Gung Ho Guns. He was charged by Knives to lead the Guns to cause Vash endless suffering in his life time. In the anime, Legato honors that request and uses the Guns to bring suffering in one way or another to Vash. In the manga though, Legato tries to use the Guns to his own advantage and kill Vash. This in turn leads Knives to cripple Legato severly before moving on.
Legato plays a crucial role in both the anime and manga. In the anime, during their final encounter, he makes a group of villagers attack and nearly execute Milly and Meryl since it would cause Vash to suffer. He does not listen to Vash's pleas and continues with his plan. In the manga, he grows stronger after his crippling effect from Knives. After Vash collects all twelve coins though that each Gung Ho Gun had, he finds that Legato's powers have been blocked.
Status: Killed by Vash in both the anime and the manga.