Genzo Makishima was the head of Chronos Japan. After being ousted he was transformed into the original Guyver Killer: Enzyme.
Genzo Makishima was the director of Chronos' Japan during the events that led to the activation of the Guyver Units. Years ago Genzo bankrupted Agito Makashima's parents leading to their deaths. He adopted Agito and raised him in his own image. The three Guyver units found at the Relic Point in Japan were to be sent to Chronos Headquarters but were stolen by an uncompleted Zoanoid transporting them to an unknown benefactor.
Unit 1 fell into the hands of Sho Fukamachi, a young student. Unit 2 would be recovered by Chronos but was accidentally actived by Inspector Oswald Lisker. Much of the data Chronos gathered was from his use of the unit. Unit 3's fate was unknown for quite some time. Eventually it was discovered activated, but its user managed to conceal their identity for quite some time.
Eventually due to his failure to capture Guyver 1, Genzo was removed as head of Chronos Japan. He was re-engineered to be a Guyver Killing Zoanoid, the prototype Zoanoid known as Enzyme. Enzyme fights Sho Fukamachi and after a lengthy battle destroys the Guyver by removing the control medal. However the armor still tries to fight Enzyme and Genzo is self detonated destroying Genzo and remains of the original unit 1.
Genzo Makishima would die never knowning his adopted son was the orchestrator of his downfall.
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