Yes. I mean the manga isn't "great", I like it, but holy crap I couldn't even finish the first season of the anime.
The anime is mostly fan service. The plot of the anime just went off tangent (I think after the school council's disciplinary squad), so it lacked major battles that the manga had. This results in less spectacular character evolutions for everyone. The anime did not pound more seriousness in the monster and human coexisting idealism.
Sadly, the anime does not do the manga series justice at all. It replaces some content in the manga (fights, character development, etc) with extra fan service shoved into the broken story they pushed in the anime.
I own Volumes One thru Ten of the Rosario + Vampire manga (first season) and they were quite a blast to read. Great character development (better than anime), more fights, more story-moving content, and better quality made it a winner hands down compared to the anime. I would highly recommend the manga series over the two anime seasons to anyone who has interest in the franchise.