Hmm. Hard to say. X burner shouldn't work due not only to Kuma's speed but the fact that he can deflect it, nor should Zero point breakthrough because Kuma is too fast for that technique to finish. On the other hand Tsna has speed and reactions to match Kuma so he isn't likely to be tagged either. Maybe Natsu's petrification scream can do the trick. Either that or Tsuna makes a mistake first. I'd have to say Tauna with effort could beat Kuma the majority of times but he isn't immune from losing.