Sage Naruto did a ok job against Pain. But not good enough to beat the three of them at the same time.
Deidara has micro bombs that causes detonation to cells.
Kakuzu has five lives and lots of nature type jutsus.
Kisame has Samehada and tailed beast level chakra.
Plus even if they start to lose Deidara also has that suicide bomb that almost killed Sasuke.
Deidara solos. Naruto can't fly so he gets wiped away by C4
Kakuzu can't do anything here but tank (Kakuzu ddidn't have the domu heart when Naruto beat him)
Kisame would eat a rasenshuriken then proceed to water dome him and all his summons can deal with 1000 sharks
@Saladking: I see, how many other times has he used his domu heart?
He used it on his arm when he punched down a giant iron gate
It blocked a suprise attack from Aoba when he threw a kunai at him
It blocked an explosion from an explosive kunai tag at close range
It blocked Choji's giant ball attack thing that made a crater
SM Naruto loses pretty badly. Kisame vs able to fight against Bee pretty well, Deidara fought a pretty close fight against Sasuke and Kakazu was going to beat Kakashi, Ino and Chouji all at the same time.
He could take them all in a 1v1 but I think the numbers game here will beat him.