No it's not. This is an awful stomp in Sasuke's favor. While I don't think Amaterasu would put Deadpool down (The guy has taken Atmosphereic re entry in a little metal ball) his superior speed, strength, and ability to chop him to pieces will.
This is a highly one-sided battle. Sasuke's vast array of elemental jutsu alone puts him in favor of winning the battle against Deadpool. A simple Kirin should be sufficient to incinerate Deadpool allowing Sasuke to walk away with the victory. In addition Sasuke's Mangekyou Sharingan abilities also grant him an advantage over Deadpool due to his capability of using Amaterasu, Tsukuyomi (Though not as well as Itachi) and Susanoo. Sasuke's physical attributes also exceed that of Deadpool's, he is physically stronger, faster and possesses more stamina than mercenary. Both are excellent fighters although Deadpool tends to come off as a joke most of the time. A simple way for Sasuke to defeat Deadpool is to either use genjutsu or Shadow Clones to distract Deadpool and hit the mercenary with a Chidori or Chidori Senbon. Even if they were both in character Sasuke would certainly win since Deadpool's character comes off as a jokester while Sasuke is cold-blooded and completely willing to kill and though he cannot kill Deadpool he could knock him unconscious etc.
@battleheiz: Sasuke might not be faster than a bullet, but he is faster than Deadpool's hand. Not to mention his Sharingan could see his arm moving to shoot at him before it even started to, so he could avoid the bullets pretty easily since Deadpool could never get a good beat on him.
Sasuke easy win here. faster, stronger, large scale attacks, pinpoint accurate attacks, attacks faster than bullets (his lightning jutsus) spidey sense-like ability, and if for some reason he went susanoo then there's literally nothing deadpool could do to him.