Rip should win this.
Blade could win if he goes in fast. I doubt Blade can tank the Magic Bullet from Rip Van Winkle like Alucard did so he needs to move fast. Blade MIGHT be fast/agile enough to dodge Rip's Magic Bullet and then go in and slice her head of with his blade. Rip to me didn't show any combat feats, she just stood still and fired her Magic Bullet so Blade takes her in combat if Rip disides to duke it out with Blade. Close battle.
Director David O Russel and Crew do the Hustle in a baroque comedic farce with some real humanity to it.