Round 1: The duo, probably.
Roumd 2: Pyron. Even without his absurd size, he's still a galaxy level threat IIRC.
Pyron with ease. While impressive with their stats, Asura and Chakravartin don't have any abilities that could get around Pyron's cosmic body (as Asura's Wrath is more known for its over-the-top destruction than any notable hax) as being made of pure energy's gonna make it very difficult for the two to connect any attacks on Pyron and connecting any energy attacks on Pyron would only strengthen him further.
Pyron's gonna make the two bitter enemies his personal bitches.