Well, I think Kars and Dio would be enough to solo, Dio was calced to have triple digit terraton time-stop damage, that's county busting, and there is nothing they can do to Kars as he would adapt to everything they did and can reform from simple air bubbles, I remember a thread where he was able to adapt to even Barragan's respira, the both also have faster than light reactions and combat speed.
The only problem I see is the range, since I don't think anyone on the Jojo side is tanking knife and fork or anything else except Kars.
However with both Dio and Diavolo being able to bypass that I don't see it a problem, Diavolo can pretty much protect his entire team and with 3 hours prep Diavolo's future readings will give him what he needs to know. Not to mention Yoshikage kira can use Another One Bites the Dust and rewind time 24 hours is things get messy, and his ability would even take out Mount Turtle with no problem, Killer Queen will bypass all their defense and everyone on this team has FTL combat and reactions speed.
So given the hax and the superior combat and versatility of team 2...
They wins with mid-low difficulty!