Of course she does. And she has pretty good reasons to be mad at Goku. First of all, she was the one who wanted to marry him, Goku just agreed to it because he thought that a bride was food. And even though he might have grown to love her over time, he doesn't show it. And let's not forget that Goku doesn't have a job leaving his family pretty poor. He also runs off to participate in fatal battles and seems more concerned with fighting and training than Chi Chi. Hell, at the end of GT he just left his family behind to go train.
for me yes i mean she's like all mad when goku's into some trouble and if he's from a fight that she's worried right and on android saga she was really worried for goku when he was attacked by the heart virus and for goku pretty much the same thing (even though at first not) i mean on the piccolo jr saga he blushed when chi chi hugged her and on cell saga they secretly kissed and he did say "i'll miss you" and at the end of the majiin buu saga he did say he loves chi chi and in some movie he did rush off when he saw chi chi was attacked